IL31RA HEK293
CBP74680
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| I. Background | |
| IL31RA（白细胞介素-31受体α亚基）是I型细胞因子受体家族成员，与OSMR（抑瘤素M受体）形成异二聚体复合物，共同构成功能性IL-31受体。该受体复合物顺利获得激活JAK1/STAT3等信号通路，在皮肤免疫、瘙痒传导以及气道平滑肌收缩中发挥关键作用。此外，IL31RA的表达还与基底样乳腺癌的进展和转移相关。 | |
| II. Description | |
| IL31RA HEK293 细胞，在 HEK293 细胞的基础上，稳定表达 IL31RA。 | |
| III. Introduction | |
| Expressed gene: | IL31RA |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10% FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant IL31RA HEK293 constitutively expressing IL31RA. |
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